Leukocyte Platelet Rich Fibrin

Leukoctye Platelet Rich Fibrin (L-PRF) is a by-product of blood (plasma) that is rich in platelets. Until now, its use has been confined to the hospital setting. This was due mainly to the cost of separating the platelets from the blood and the large amount of blood needed to produce a suitable quantity of platelets. New technology permits doctors to harvest and produce a sufficient quantity of platelets from only 55 cc of blood, which is drawn from the patient while they are having outpatient surgery.

Why All The Excitement About L-PRF?

L-PRF permits the body to take advantage of the normal healing pathways at a greatly accelerated rate. During the healing process, the body rushes many cells and cell-types to the wound in order to initiate the healing process. One of those cell types is platelets. Platelets perform many functions, including formation of a blood clot and release of growth factors (GF) into the wound. These growth factors; platelet derived growth factors (PDGF), transforming growth factor beta (TGF), and insulin-like growth factor (ILGF), function to assist the body in repairing itself by stimulating stem cells to regenerate new tissue. The more growth factors released and sequestered into the wound, the more stem cells are stimulated to produce new tissue. Thus, L-PRF permits the body to heal faster and more efficiently.

A subfamily of TGF, is bone morphogenic protein (BMP). BMP has been shown to induce the formation of new bone in research studies in both animals and humans. This is of great significance to the surgeon who places dental implants. By adding L-PRF, and BMP, to the implant site with bone substitute particles, the implant surgeon can now grow bone more predictably and faster than ever before.

L-PRF Has Many Clinical Applications

L-PRF can be used to aid Bone grafting for dental implants. This includes onlay and inlay grafts, sinus lift procedures, ridge augmentation procedures, closure of cleft and/or lip, and palate defects. It can also assist in repair of bone defects created by removal of teeth, or small cysts and repair of fistulas between the sinus cavity and mouth.

L-PRF Also Has Many Advantages

Safety: L-PRF is a by-product of the patient’s own blood, therefore, disease transmission is not an issue.

Convenience: L-PRF can be generated in the doctor’s office while the patient is undergoing an outpatient surgical procedure such as the placement of dental implants.

Faster healing: The supersaturation of the wound with L-PRF, and thus growth factors, produces an increase of tissue synthesis and faster tissue regeneration.

Cost effectiveness: Since L-PRF harvesting is done with only 55 cc of blood in the doctor’s office, the patient need not incur the expense of the harvesting procedure in hospital or at a blood bank.

Ease of use: L-PRF is easy to handle and actually improves the ease of application of bone substitute materials and bone grafting products by making them more gel-like.

Frequently Asked Questions About L-PRF

Is L-PRF safe? Yes. During the outpatient surgical procedure a small amount of your own blood is drawn out via the IV. This blood is then placed in the L-PRf centrifuge machine and spun down. In less than 15 minutes, the L-PRF is formed and ready to use.

Should L-PRF be used in all bone-grafting cases? Not always. In some cases, there is no need for L-PRF. However, in the majority of cases, application of L-PRF to the graft will increase the final amount of bone present, in addition to making the wound heal faster and more efficiently.

Will my insurance cover the costs? Unfortunately not. The cost of the L-PRF application (approximately $200) is paid by the patient.  It is significantly less expensive, easier to process and more effective than Platelet Rich Plasma (PRP)

Can L-PRF be used alone to stimulate bone formation? No. L-PRF must be mixed with either the patient’s own bone, a bone substitute material such as demineralized freeze-dried bone, or a synthetic bone product, such as BIO-OSS.

Are there any contraindications to L-PRF? Very few. Obviously, patients with bleeding disorders or hematologic diseases do not qualify for this in-office procedure. Check with your surgeon and/or primary care physician to determine if PRP is right for you.

Cortland Oral Surgery

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We had an excellent experience from start to finish for my daughter’s wisdom teeth extraction. The front office staff was exceptionally helpful with insurance questions and general questions about the procedure. The medical staff (doctor and nurses) were excellent. They also give you a booklet spelling out exactly what you need to do for follow-up care. I couldn’t have been happier with how things went.

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Had an appointment scheduled the week prior but came down with a severe cold. Was given the option of keeping the appointment or rescheduling for less than a week later, which I did. The procedure went very smoothly which led to a very easy recovery.

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I’ve had 2 teeth pulled by this Doctor and he’s done a great job both times. Everyone is nice.

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excellent, thoroughly professional in every way, I have highly recommended

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The staff was very nice, and the doctor was fantastic. He's also very funny, which put me at ease. Highly recommended!

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The doctor was timely and has a good sense of humor. Would recommend the doctor.

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The entire office was very friendly and put my son at ease during his wisdom tooth extractions.

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The procedure was carried out with efficiency, care for my comfort and disclosure of follow-up options. The paperwork for after-care was comprehensive. So far so good on recovery. As pleasant an experience as can be expected for a tooth extraction.

- Ed B

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Our son was referred to Cortland Oral Surgery as a less expensive alternative to a local oral surgeon for removal of all four wisdom teeth. The price was about half what we were quoted by the other O.S., but the quality of care was not lacking at all. At his initial appointment, actual surgery day and follow appointment he was seen promptly, the staff is exceptionally friendly and helpful. There wasn't a single issue or problem after our son had his teeth pulled. I would highly recommend this practice to anyone needing specialized dental care.

- Jen D

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Excellent place. Everything was pleasant.

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Very professional, efficient and personal.

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Everything went better than expected!

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Great!

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I was so nervous when I got there. But as soon as I was called to the room and talked to the assistant and doctor I knew it would be fine

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Everyone was very kind and the Doctor’s sense of humor helped me through a stressful situation.

- Gretchen G

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I had and excellent experience. I was not looking forward to having a tooth pulled. I was anxious. But during the whole procedure it wasn’t as bad as I thought. I loved Dr. Sangiacomo and his technique, and professionalism, and he had a nice way of talking to me to make me feel less anxious. Once it was over, I was like, your finished! A much better experience than any other teeth I had extracted in my lifetime.

- Constance A

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I’m not a fan of oral surgery at all! I actually passed out after I left! However, the staff & doctor were friendly & did a great job! I would definitely recommend this office if you’re in need of oral surgery!

- Angie P

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This is a very efficient group of professionals. They clearly explained the procedure and did everything they could to make me as comfortable as possible. I am very impressed.

- Hal F

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I was scared to be going in to get my wisdom teeth out without getting any anesthesia. The assistant talked me and eased my mind before the first shot of novacane. It only took about an hour to have all 4 wisdom teeth removed. All I felt was pressure. No pain at all during the procedure. Highly recommend to anyone who meeds work done on their teeth.

- Caytlyn B

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Wonderful experience all around. Doctor and staff are top notch! Thank you

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