Leukocyte Platelet Rich Fibrin

Leukoctye Platelet Rich Fibrin (L-PRF) is a by-product of blood (plasma) that is rich in platelets. Until now, its use has been confined to the hospital setting. This was due mainly to the cost of separating the platelets from the blood and the large amount of blood needed to produce a suitable quantity of platelets. New technology permits doctors to harvest and produce a sufficient quantity of platelets from only 55 cc of blood, which is drawn from the patient while they are having outpatient surgery.

Why All The Excitement About L-PRF?

L-PRF permits the body to take advantage of the normal healing pathways at a greatly accelerated rate. During the healing process, the body rushes many cells and cell-types to the wound in order to initiate the healing process. One of those cell types is platelets. Platelets perform many functions, including formation of a blood clot and release of growth factors (GF) into the wound. These growth factors; platelet derived growth factors (PDGF), transforming growth factor beta (TGF), and insulin-like growth factor (ILGF), function to assist the body in repairing itself by stimulating stem cells to regenerate new tissue. The more growth factors released and sequestered into the wound, the more stem cells are stimulated to produce new tissue. Thus, L-PRF permits the body to heal faster and more efficiently.

A subfamily of TGF, is bone morphogenic protein (BMP). BMP has been shown to induce the formation of new bone in research studies in both animals and humans. This is of great significance to the surgeon who places dental implants. By adding L-PRF, and BMP, to the implant site with bone substitute particles, the implant surgeon can now grow bone more predictably and faster than ever before.

L-PRF Has Many Clinical Applications

L-PRF can be used to aid Bone grafting for dental implants. This includes onlay and inlay grafts, sinus lift procedures, ridge augmentation procedures, closure of cleft and/or lip, and palate defects. It can also assist in repair of bone defects created by removal of teeth, or small cysts and repair of fistulas between the sinus cavity and mouth.

L-PRF Also Has Many Advantages

Safety: L-PRF is a by-product of the patient’s own blood, therefore, disease transmission is not an issue.

Convenience: L-PRF can be generated in the doctor’s office while the patient is undergoing an outpatient surgical procedure such as the placement of dental implants.

Faster healing: The supersaturation of the wound with L-PRF, and thus growth factors, produces an increase of tissue synthesis and faster tissue regeneration.

Cost effectiveness: Since L-PRF harvesting is done with only 55 cc of blood in the doctor’s office, the patient need not incur the expense of the harvesting procedure in hospital or at a blood bank.

Ease of use: L-PRF is easy to handle and actually improves the ease of application of bone substitute materials and bone grafting products by making them more gel-like.

Frequently Asked Questions About L-PRF

Is L-PRF safe? Yes. During the outpatient surgical procedure a small amount of your own blood is drawn out via the IV. This blood is then placed in the L-PRf centrifuge machine and spun down. In less than 15 minutes, the L-PRF is formed and ready to use.

Should L-PRF be used in all bone-grafting cases? Not always. In some cases, there is no need for L-PRF. However, in the majority of cases, application of L-PRF to the graft will increase the final amount of bone present, in addition to making the wound heal faster and more efficiently.

Will my insurance cover the costs? Unfortunately not. The cost of the L-PRF application (approximately $200) is paid by the patient.  It is significantly less expensive, easier to process and more effective than Platelet Rich Plasma (PRP)

Can L-PRF be used alone to stimulate bone formation? No. L-PRF must be mixed with either the patient’s own bone, a bone substitute material such as demineralized freeze-dried bone, or a synthetic bone product, such as BIO-OSS.

Are there any contraindications to L-PRF? Very few. Obviously, patients with bleeding disorders or hematologic diseases do not qualify for this in-office procedure. Check with your surgeon and/or primary care physician to determine if PRP is right for you.

Cortland Oral Surgery

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Our Latest Patient Testimonial

Not sure if my previous review was received so have done a second one. Walked in after being referred by my dentist to get information on tooth extraction. Worked out that they could take me in that afternoon. With less time to worry, all the staff were professional, courteous and very calming. The doctor walked me through the procedure to extract a tooth and put my nerves at ease. Would recommend them to anyone, very pleased. Thank you to all.

- Marlene R

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I wasnt very brave when it came to the needles but they were very good about it and actually had someone hold my hand during it to help. They got me in right away, i had all 4 wisdom teeth pulled, and i was out in about an hour. They have a very kind and well working staff and i would tell anyone who needs teeth work to go here.

- Marjorie T

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Your staff was very friendly and professional. Dr SanGiacomo made me feel comfortable. I had a tooth extraction with minimal discomfort.

- Andrew C

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I had a very pleasant experience and will go back when necessary.

- Rita O

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The extraction was quick and painless

- Margaret B

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Doctor SanGiacomo made a challenging extraction much less stressful with his patience and good humor. Everything came out all right in the end, despite deep roots and brittle tooth.

- Amy S

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I dont have a single bad thing to say. Staff and Doctor were fantastic. Truly wonderful

- Tim S

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Felt at ease during my procedure

- Megan H

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Even though I did not want to be there - the staff and doctor did a fine job!!

- Diane B

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I would recommend Cortland Oral Surgery to anyone who needs procedures done. They have very friendly staff and the work is performed quickly but with great care and attention to detail.

- Hunter S

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Everyone was so nice and friendly. Very pleasant experience. Wonderful Dr. and Staff!

- Cynthia R

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We were happy with the quality of service received for this medical procedure. We were pleasantly surprised by a family discount due to another sibling having the procedure done previously.

- Erin B

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Wonderful service. Made me feel comfortable. Pretty much painless surgical extraction. Professional staff. Highly recommend this doctor.

- John E

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Excellent service and fast

- Richard C

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These people made a stressful, normally uncomfortable procedure all most fun! Very appreciative.

- JOHN A

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Wonderful staff, the dentist was very gentle, and funny too! I went in anxious as ever, but was soon at ease. Very little pain and swelling the days following 3 teeth extractions.

- Adajean W

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Very good experience everyone was very professional and friendly. If I ever need an oral surgeon again I would definitely go back.

- Cindy C

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Everyone in the office is wonderful! They've exceeded my expectations and made the process as easy and affordable as possible. I would (and have) highly recommend Dr. SanGiacomo to anyone who needs work done.

- Raechel A

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very pleased

- Ronald B

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Great experience with a difficult procedure! Thank you!

- Carter F

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