Leukocyte Platelet Rich Fibrin

Leukoctye Platelet Rich Fibrin (L-PRF) is a by-product of blood (plasma) that is rich in platelets. Until now, its use has been confined to the hospital setting. This was due mainly to the cost of separating the platelets from the blood and the large amount of blood needed to produce a suitable quantity of platelets. New technology permits doctors to harvest and produce a sufficient quantity of platelets from only 55 cc of blood, which is drawn from the patient while they are having outpatient surgery.

Why All The Excitement About L-PRF?

L-PRF permits the body to take advantage of the normal healing pathways at a greatly accelerated rate. During the healing process, the body rushes many cells and cell-types to the wound in order to initiate the healing process. One of those cell types is platelets. Platelets perform many functions, including formation of a blood clot and release of growth factors (GF) into the wound. These growth factors; platelet derived growth factors (PDGF), transforming growth factor beta (TGF), and insulin-like growth factor (ILGF), function to assist the body in repairing itself by stimulating stem cells to regenerate new tissue. The more growth factors released and sequestered into the wound, the more stem cells are stimulated to produce new tissue. Thus, L-PRF permits the body to heal faster and more efficiently.

A subfamily of TGF, is bone morphogenic protein (BMP). BMP has been shown to induce the formation of new bone in research studies in both animals and humans. This is of great significance to the surgeon who places dental implants. By adding L-PRF, and BMP, to the implant site with bone substitute particles, the implant surgeon can now grow bone more predictably and faster than ever before.

L-PRF Has Many Clinical Applications

L-PRF can be used to aid Bone grafting for dental implants. This includes onlay and inlay grafts, sinus lift procedures, ridge augmentation procedures, closure of cleft and/or lip, and palate defects. It can also assist in repair of bone defects created by removal of teeth, or small cysts and repair of fistulas between the sinus cavity and mouth.

L-PRF Also Has Many Advantages

Safety: L-PRF is a by-product of the patient’s own blood, therefore, disease transmission is not an issue.

Convenience: L-PRF can be generated in the doctor’s office while the patient is undergoing an outpatient surgical procedure such as the placement of dental implants.

Faster healing: The supersaturation of the wound with L-PRF, and thus growth factors, produces an increase of tissue synthesis and faster tissue regeneration.

Cost effectiveness: Since L-PRF harvesting is done with only 55 cc of blood in the doctor’s office, the patient need not incur the expense of the harvesting procedure in hospital or at a blood bank.

Ease of use: L-PRF is easy to handle and actually improves the ease of application of bone substitute materials and bone grafting products by making them more gel-like.

Frequently Asked Questions About L-PRF

Is L-PRF safe? Yes. During the outpatient surgical procedure a small amount of your own blood is drawn out via the IV. This blood is then placed in the L-PRf centrifuge machine and spun down. In less than 15 minutes, the L-PRF is formed and ready to use.

Should L-PRF be used in all bone-grafting cases? Not always. In some cases, there is no need for L-PRF. However, in the majority of cases, application of L-PRF to the graft will increase the final amount of bone present, in addition to making the wound heal faster and more efficiently.

Will my insurance cover the costs? Unfortunately not. The cost of the L-PRF application (approximately $200) is paid by the patient.  It is significantly less expensive, easier to process and more effective than Platelet Rich Plasma (PRP)

Can L-PRF be used alone to stimulate bone formation? No. L-PRF must be mixed with either the patient’s own bone, a bone substitute material such as demineralized freeze-dried bone, or a synthetic bone product, such as BIO-OSS.

Are there any contraindications to L-PRF? Very few. Obviously, patients with bleeding disorders or hematologic diseases do not qualify for this in-office procedure. Check with your surgeon and/or primary care physician to determine if PRP is right for you.

Cortland Oral Surgery

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Was so nervous about having tooth pulled but I never felt a thing, just a few pricks from the needle used to numb me up! Well done!

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Dr SanGiacamo made me feel at ease! He made sure I was comfortable and very numb before he started the procedure. He was quick and efficient.

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Great

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Had a great experience at Cortland Oral Surgery. It's generally not a good thing when you need to see an oral surgeon, but Dr. SanGiacomo and his team made the visit a real pleasure.

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Everyone was very nice. Don't even remember being knocked out and they wheeled me out to my car after the procedure was done.

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very happy with my complete visit was nervous the nurse put me at ease she explained whole procedure the dr made sure i was comfortable i would recommend your service

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Dr. Sangiacomo is a quite talented oral surgeon, with a good bedside manner!

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Very friendly and professional - We had a very good experience

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An excellent experience.

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Fabulous service, care and courtesy. I highly recommend. Thank you.

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I put off my wisdom teeth surgery for seven years due to extreme anxiety. When they inevitably had to come out, I ended up having an amazing experience with Cortland Oral Surgery! The staff were all very friendly and helpful, and Dr. SanGiacomo has a sense of humor and a way with patients that really makes you feel at ease. I waited no more than a few minutes between checking in and getting into the chair. My IV was placed, and the next thing I remember, the whole procedure was over. My recovery has been a breeze so far and I had very little bleeding or pain. I would definitely recommend this office to anyone seeking oral surgical care.

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Fast easy and painless for the first time ever at a dentist

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I would definitely recommend this office to anyone who will listen. Words that I never thought I would say ..., I love this dentist and staff.

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I would not hesitate to recommend Dr. SanGiacomo. It is never pleasant to have dental procedures, but Dr. SanGiacomo and his staff did their best to alleviate my anxiety. What I thought would be a painful procedure was actually almost pain free. Thanks to everyone in the office...I appreciate your courtesy and professionalism.

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I would highly recommend this office to anyone in need of oral surgery. They are very professional and good at what they do.

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This dentist is absolutley amazing. The staff we great. They all left a great lasting impression. My 15 year old daughter loved them too.

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